it's a trying world down there in the nucleus (unless you're mitochondrial DNA--they live on easy street). DNA isn't having an emotional day. It's just our old friend Brownian motion--he never stops moving in a fluctuating random dance. Also, Brownian motion might be a girl, no one knows for sure.
Well, Adam E. Cohen decided to do something about it. Yes, researchers have had some success in countering that infernal microscopic jiggle, but Dr. Cohen and his colleagues at Harvard been trying to look closely at the dynamics of DNA trapped inside of a microfluidic channel.
At the Industrial Physics Forum (part of the AVS annual meeting) in Boston last Monday, Dr. Cohen presented a lecture entitled "Single Molecule Imaging, Anti-Brownian Electrokinetic Trap."
Cohen is working with William E. Moerner at Stanford to discover the shape of a DNA molecule, how it deviates from an average shape, and the dynamics of how it moves from shape to shape. The results look very similar to different energy levels of electron orbits. I think. Maybe. Don't quote me on that. To see the pretty pictures yourself, take a look at this article published in PNAS last year.
